Conclusion Despite the abundant knowledge acquired through research and clinical practice, any patient’s response to medication therapy is multifactorial and not fully predictable. The added complexities of medication management in an aging patient population include incremental disease burdens, cognitive and organ system declines, and various other physiologic and social determinants of health. Risks for medication misadventure are often escalated in acute and long-term care settings and 2019 AGS Beers Criteria Update Expert Panel. (2019). American Geriatrics Society 2019 updated AGS Beers Criteria for potentially inappropriate medication use in older adults . Journal of the American Geriatrics Society , 67 (4), 674-694. https://doi.org/ 10.1111/ jgs.15767 • 2023 AGS Beers Criteria Update Expert Panel. (2023). American Geriatrics Society 2023 updated AGS Beers Criteria for potentially inappropriate medication use in older adults. 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