Texas Pharmacy Ebook Continuing Education

Table 4. Glycemic Targets for Nonpregnant Adults with Diabetes and without Limited Life Expectancy American Diabetes Association (ADA)

American Association of Clinical Endocrinologists (AACE)

Fasting and preprandial blood glucose (mg/dL)

80–130

<110

Postprandial blood glucose (mg/dL)

<180; 2 hours after start of a meal

<140; 2 hours after the start of a meal

A1C (%)

<7.0 without hypoglycemia

<6.5

Adapted from American Diabetes Association 3 . Adapted from Comparison of the diabetes guidelines from the ADA/EASD and the AACE/ACE 21 . Structured BGM with a glucometer

Knowing your actual blood glucose can be a powerful motivator to improve glycemic management. When a patient sees that their blood glucose level is above or below target, this may impact their selection of food intake and activity level as well as use of or dose of medication. The data from BGM enables patients to make decisions based on current glycemic management. Using a structured approach to BGM (checking blood glucose lev- els at the same time every day) has effectively reduced A1C levels among patients performing BGM compared to those who do not perform BGM22. Structured BGM allows visualization of glycemic levels by allowing patients to record the results on a log or view on a graph that some glucometers now provide on their screen. The visualization of glycemic levels facilitates understanding of the impact of diet choices, activity level, and medication use on blood glucose levels. An example of structured

testing for BGM for patients with type 1 and type 2 diabetes is displayed in Figure 8. Structured testing for BGM in patients with intensive insulin regimens requires patients to test a minimum of seven times/day for 3 to 4 days. Structured testing involves check- ing before and 2 hours after each meal and at bedtime. Consider a case in which BGM for a person with type 1 diabetes reveals episodes of hypoglycemia before breakfast on Saturday and Sunday. Perhaps considering reducing their premeal insulin dose before breakfast is a consideration. In addition, if all post- dinner blood glucose values are above the target range of 180 mg/dL, an addition of medication may assist with glycemic man- agement. Collecting data for 3 to 4 days provides an overview of blood glucose values and patterns. Next, consider a case in which BGM for a person with type 2 dia- betes reveals prebreakfast, pre-lunch, and predinner data within target ranges. However, post-meal values are above target rang- es. These data suggest the person with diabetes needs more medication to manage their post– blood glucose excursions.

Figure 8. Structured Blood Glucose Monitoring Testing for Persons With Type 1 Diabetes Breakfast Lunch

Dinner

Bedtime

BB

AB

BL

AL

BD

AD

BT

Monday Tuesday

80

136 142 138 122 116 132 122

122 132 130 126 118 132 130

244 192 264 252 258 196 272

106 110

Wednesday

Thursday

92 74 70 68

Friday

Saturday Sunday

Structured Blood Glucose Monitoring Testing for Persons With Type 2 Diabetes Breakfast Lunch

Dinner

Bedtime

BB

AB

BL

AL

BD

AD

BT

Monday Tuesday

210

130

Wednesday

236

Thursday

142

Friday

263

Saturday

128

Sunday Note: BB: before breakfast; AB: after breakfast; BL: before lunch; AL: after lunch; BD: before dinner; AD: after dinner; BT: bedtime Note: All blood glucose values in the figure are mg/dL

There are many reasons for checking pre- and postprandial blood glucose levels. Knowing the premeal blood glucose may lead a patient to modify their food intake (especially if it is elevated be- fore the meal) and to take a specific dose of insulin. Comparing the premeal blood glucose to a 2-hour postprandial blood glu- cose helps one to discern the impact of the food eaten on the

blood glucose level. If using insulin, comparison of the pre- and post–blood glucose helps determine the appropriateness of the insulin dose. It is important for people with diabetes to learn how to interpret and evaluate blood glucose values to best adjust food intake, physical activity, and medications. Understanding blood glucose

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Book Code: RPTX3024

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