____________________________________________________ Medical Marijuana and Other Cannabinoids
F inal E xam
MEDICAL MARIJUANA AND OTHER CANNABINOIDS
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111. The evolution of Cannabis sativa has been traced to A) Northern Africa. B) remote regions of South America.
117. The relative concentration of THC, cannabidiol (CBD), and other cannabinoids in a given cannabis plant is influenced by A) cannabis strain. B) cultivation techniques. C) soil and climate conditions. D) All of the above 118. Which of the following statements regarding dronabinol is TRUE? A) The brand name is Cesamet. B) It is available only as an oromucosal spray. C) It is an isomer of THC, shown to be chemically identical to plant-derived THC. D) It was initially approved for the treatment of anorexia and cachexia in patients with AIDS. 119. Legal medicinal cannabis purchased from dispensaries in the United States is regulated to a potency of
C) the Central Asian/Himalayan region. D) horticultural experiments conducted in Europe in the 1950s.
112. In the United States, the first medical conference on cannabis was held in 1860 by the A) Ohio State Medical Society. B) American Medical Association.
C) California State Board of Medicine. D) U.S. Food and Drug Administration.
113. The first state to legally approve the use of cannabis for medical purposes was A) Ohio.
B) Vermont. C) Colorado. D) California.
A) 9% THC/9.5% CBD. B) 22% THC/0.7% CBD. C) 13.5% THC/less than 1% CBD. D) Medicinal cannabis in the United States lacks government-controlled standardization of potency and purity.
114. The endogenous cannabinoid system (ECS) helps regulate all of the following, EXCEPT:
A) Respiration B) Bone density C) Aversive memory extinction D) Inflammation in pain circuits and cascades
120. CBD has been found to A) negatively affect memory.
B) have limited therapeutic potential. C) display significant psychoactive properties. D) have greater antioxidant activity than ascorbic acid (vitamin C) and tocopherol (vitamin E).
115. The most abundant G-protein-coupled receptors in the brain are A) CB1 receptors. B) CB2 receptors. C) GPR55 receptors. D) peroxisome proliferator-activated receptors (PPARs).
121. With smoked cannabis, the maximal effect occurs in
A) 30 seconds. B) 30 minutes. C) 2 to 3 hours. D) 6 hours.
116. CB2 receptor activation acts to
A) inhibit cytokine and chemokine release. B) inhibit release from inhibitory opioid synapses. C) facilitate neutrophil and macrophage migration. D) stimulate proinflammatory cytokine production.
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