A third group are the protease inhibitors (PIs) which block protease, another enzyme that the virus needs to make copies of itself. Drugs in this class include: Generic Name Brand Name FDA Approval Date Atazanavir (atazanavir sulfate, ATV) Reyataz June 20, 2003 Darunavir (darunavir ethanolate, DRV) Prezista June 23, 2006
CCR5 antagonists work to block CCR5 coreceptors on the surface of certain immune cells that HIV needs to enter the cells. There is one drug in this class: Generic Name Brand Name FDA Approval Date Maraviroc (MVC) Selzentry August 6, 2007 Integrase inhibitors block HIV integrase, another enzyme HIV needs to make copies of itself. These include: Generic Name Brand Name FDA Approval Date Dolutegravir (dtg, dolutegravir sodium) Tivicay August 13, 2013
Fosamprenavir (fosamprenavir calcium, FOS-APV, FPV)
Lexiva
October 20, 2003
Raltegravir (raltegravir potassium, ral)
Isentress
October 12, 2007
Ritonavir (RTV)
Norvir
March 1, 1996
Isentress HD May 26, 2017
Saquinavir (saquinavir mesylate, SQV)
Invirase
December 6, 1995
Post-attachment inhibitors block CD4 receptors on the surface of certain immune cells that HIV needs to enter the cells: Generic Name Brand Name FDA Approval Date Ibalizumab-uiyk (Hu5A8, IBA, Ibalizumab, TMB- 355, TNX-355) Trogarzo March 6, 2018 Pharmacokinetic enhancers are used in HIV treatment to increase the effectiveness of an HIV medicine included in an HIV regimen. These include: Generic Name Brand Name FDA Approval Date Cobicistat (COBI, c) Tybost September 24, 2014
Tipranavir (TPV)
Aptivus
June 22, 2005
Fusion inhibitors block the virus from entering the CD4 cells of the immune system. One drug is in this class: Generic Name Brand Name FDA Approval Date Enfuvirtide (T-20) Fuzeon March 13, 2003
Combination HIV medicines contain two or more HIV medicines from one or more drug classes. This is a large class including: Generic Name Brand Name FDA Approval Date Abacavir and lamivudine (abacavir sulfate / lamivudine, ABC / 3TC) Epzicom August 2, 2004 Abacavir, dolutegravir, and lamivudine (abacavir sulfate / dolutegravir sodium / lamivudine, ABC / DTG / 3TC) Triumeq August 22, 2014 Abacavir, lamivudine, and zidovudine(abacavir sulfate / lamivudine / zidovudine, ABC / 3TC / ZDV) Trizivir November 14, 2000 Atazanavir and cobicistat (atazanavir sulfate / cobicistat, ATV / COBI) Evotaz January 29, 2015 Bictegravir, emtricitabine, and tenofovir alafenamide (bictegravir sodium / emtricitabine / tenofovir alafenamide fumarate, BIC / FTC / TAF) Biktarvy February 7, 2018 Darunavir and cobicistat (darunavir ethanolate / cobicistat, DRV / COBI) Prezcobix January 29, 2015 Darunavir, cobicistat, emtricitabine, and tenofovir alafenamide (darunavir ethanolate Symtuza July 17, 2018
/ cobicistat / emtricitabine / tenofovir AF, darunavir ethanolate / cobicistat / emtricitabine / tenofovir alafenamide, darunavir / cobicistat / emtricitabine / tenofovir AF, darunavir / cobicistat / emtricitabine / tenofovir alafenamide fumarate, DRV / COBI / FTC / TAF) Dolutegravir and lamivudine (dolutegravir sodium / lamivudine, DTG / 3TC) Dolutegravir and rilpivirine (dolutegravir sodium / rilpivirine hydrochloride, DTG / RPV) Doravirine, lamivudine, and tenofovir disoproxil fumarate (doravirine / lamivudine / TDF, doravirine / lamivudine / tenofovir DF, DOR / 3TC / TDF) Efavirenz, emtricitabine, and tenofovir disoproxil fumarate (efavirenz / emtricitabine / tenofovir DF, EFV / FTC / TDF) Efavirenz, lamivudine, and tenofovir disoproxil fumarate (EFV / 3TC / TDF) Efavirenz, lamivudine, and tenofovir disoproxil fumarate (EFV / 3TC / TDF)
Dovato Juluca
April 8, 2019
November 21, 2017
Delstrigo
August 30, 2018
Atripla
July 12, 2006
Symfi
March 22, 2018 February 5, 2018
Symfi Lo
EliteLearning.com/Cosmetology
Book Code: CFL0425
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