Antibiotics Review _ __________________________________________________________________________
F inal E xam
ANTIBIOTICS REVIEW
Select the best answer for each question and mark your answers on the Final Examination Answer Sheet found on page 107, or complete your test online at BOOK.CME.EDU. A passing grade of at least 70% must be achieved in order to receive credit for this course.
51. Which of the following classes of antibiotics is associated with a risk for developing Clostridioides difficile -associated diarrhea?
56. The antibacterial effect of penicillins is caused by the drugs’ action of
A) inhibiting protein synthesis. B) impairing cell wall synthesis.
A) Macrolides B) Quinolones
C) blocking the binding of aminoacyl transfer-RNA. D) displacing cations that link phospholipids together.
C) Cephalosporins D) All of the above
57. Labeled uses for the natural penicillins include treatment of infections of the A) eye. B) meninges. C) gastrointestinal tract. D) upper and lower respiratory tracts.
52. Bacteria become resistant to the effects of antibiotics by A) altered cellular permeability.
B) increased efflux of the antibiotic from the cell. C) elaboration of deactivating enzymes that alter interactions at binding sites. D) All of the above
58. Which of the following is an absolute
contraindication for administering penicillins? A) Severe renal failure B) Severe hepatic failure C) Prior allergic reaction to a member of the class D) All of the above
53. Which of the following are common ways for bacteria to gain antibiotic resistance? A) Genetic mutations B) Transfer of genetic information on plasmids C) Both A and B D) None of the above 54. The first oxazolidinone created, which was developed in an attempt to stay ahead of the developing bacteria resistance, was
59. Which of the following is considered a first- generation cephalosporin?
A) Cefixime B) Cefepime C) Cefadroxil D) Loracarbef
A) linezolid. B) cefprozil.
60. What route of elimination is used by members of the cephalosporin class of antibiotics? A) Renal B) Mixed renal/hepatic C) Hepatic metabolism with excretion into the bile D) All of the above
C) norfloxacin. D) meropenem.
55. What recommendation has the CDC made regarding infection control to minimize the spread of antibiotic resistances among patients in hospitals and residential care facilities? A) Tailor treatment plans to the most likely pathogens B) Proper hand washing during and after patient care and implementation of hospital infection control programs C) Proper use of invasive medical devices only when they are necessary D) All of the above
61. Probenecid increases serum levels of which cephalosporin? A) Cefotetan
B) Cefotaxime C) Ceftriaxone D) All of the above
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MDTX2026
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