Rhode Island Physician Ebook Continuing Education

_______________________________ Alzheimer Disease and Dementias: Early Detection and Care Planning

TYPES OF DEMENTIA

Disease

Symptoms

Attributes/Causation

Parkinson disease

Poor executive function Trouble walking, unstable gait Impaired responsiveness to visual cues Speech impairment Impaired affect/modified facial expression Decreased eye blinking Depression Confusion Insomnia Rigidity/freezing, tremor Alzheimer disease traits (memory loss, confusion, and language changes) Frontal lobe brain cell damage due to nerve damage Diagnosis confirmed postmortem Drastic change in behavior and personality Aggression Loss of speech Loss of decision-making ability Loses sense of self-awareness Patient will become completely dependent Progressive dementia Affects ability to think, reason, and process information Impaired movement, mood, and behavior

Basal ganglia cells die, causing dopamine levels to drop Progressive, chronic disease Personalized treatments for symptom relief Exercise can improve symptoms and may protect the brain No cure

Frontotemporal dementia (FTD)

Frontal lobe controls language and personality Also known as Pick disease No cure

Lewy body dementia (LBD)

1.4 million people living with this disease Due to unusual deposits of alpha-synuclein protein on brain Initial diagnosis may be mental/psychological health No cure Caused by constriction or breakdown of blood vessels in and around the brain Can be the result of a stroke(s) Lifestyle factors (diet, lack of movement, smoking) contribute to disease progression Disease can be allayed by exercise, diet, avoiding alcohol and smoking Originally referred to as punch drunk syndrome Caused by extensive hits to the head Brain has tau protein like Alzheimer disease, but presents uniquely in CTE Some symptoms can be addressed with medication Diagnosed postmortem No cure

Parkinsonian-like rigidity Hallucinations, paranoia

Vascular dementia

Problems with reasoning Impacted judgement, memory, and other thought processes Symptoms vary by location of actual constriction

Chronic traumatic encephalopathy (CTE)

Memory loss, confusion Mood disorder, personality changes, rage Can present in mid-life Person becomes erratic and unpredictable

Atypical Alzheimer disease

Amnestic problems Unusually early symptoms impacting executive and motor functioning Similar to Alzheimer disease or other form of dementia Varied symptoms suggest multiple forms of dementia

Frontal variant of Alzheimer disease Posterior cortical atrophy

Mixed dementia

Most often diagnosed as Alzheimer disease Co-existing pathology, such as blood clots or vascular disease, found postmortem Impacted by relationship between cognitive function and underlying brain abnormalities

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MDRI2026

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