Opioid Use Disorder __________________________________________________________________________
22. Which of the following is NOT a sign of acute opioid intoxication? A) Slurred speech
29. Which of the following statements regarding ultra- rapid opioid detoxification (UROD) is TRUE? A) Serious life-threatening events can occur during UROD. B) UROD has been subjected to the established process of scientific evaluation. C) UROD is recommended because potential benefits outweigh the risks and expense. D) UROD can achieve complete resolution of withdrawal symptoms through restoration of neurobiologic homeostasis.
B) Improved attention and memory C) Drowsiness or loss of consciousness D) Decreased respiration and heart rate
23. In terms of endocrine function, opioid use is associated with A) hypergonadism.
B) growth hormone abnormalities. C) increased bone mineral density. D) All of the above
30. Studies have shown one-year treatment retention rates in methadone programs of
A) 25%. B) 50%. C) 80%. D) 100%.
24. Which of the following is a sequela of nonfatal opioid overdose? A) Hepatitis B) Kidney failure C) Acute cardiomyopathy D) Significant increase in tidal volume 25. Heroin withdrawal symptoms typically begin A) 2 hours after the last dose. B) 4 hours after the last dose. C) 8 hours after the last dose. D) 24 hours after the last dose. 26. Which of the following statements regarding pain and prescribed opioids is FALSE? A) Opioids are overprescribed for legitimate pain. B) Physician overconcern of patient addiction leads to substantial undertreatment of pain. C) Patients without a history of opioid abuse are unlikely to become addicted to short-term opioid treatment. D) Long-term opioid treatment results in rates of dependence that are comparable to those seen in the population as a whole. 27. Which of the following drugs is considered the criterion standard in reversing respiratory depression and coma in acute opioid overdose? A) LAAM B) Naloxone C) Methadone D) Buprenorphine
31. Methadone maintenance is initiated at a dose of A) 5–10 mg. B) 25–30 mg. C) 60–120 mg. D) 120–240 mg. 32. Compared with methadone, buprenorphine has a A) lower risk of overdose. B) shorter duration of action. C) more severe withdrawal syndrome following cessation. D) All of the above 33. Buprenorphine is most effective at a dose of A) 2 mg. B) 5 mg. C) 10 mg. D) 12 mg or greater. 34. Which of the following statements regarding abstinence-oriented therapies for opioid dependence is TRUE? A) Long-term outcomes are good. B) The goal is total abstinence from all opioids. C) Abstinence is achieved in one phase, detoxification. D) All of the above
35. Twelve-step programs are based on A) an emphasis on total abstinence.
28. The opioid agonist most frequently used in opioid withdrawal is
B) spiritual growth, personal responsibility, and helping other addicts. C) the viewpoint that opioid abuse and dependence is a chronic, progressive disease. D) All of the above
A) LAAM. B) naloxone. C) methadone. D) buprenorphine.
Self-Assessment questions continue on next page
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MDRI2026
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